These drugs work by boosting the activity of a chemical called gamma-aminobutyric acid GABA in the brain. GABA helps calm the nerves by inducing feelings of relaxation. Most severe or fatal overdoses happen when Xanax is taken with other drugs — especially opioid pain medications — or alcohol. They may recommend an alternative medication. The prescribed amount typically ranges from 0. This amount may be split between three doses throughout the day. Your doctor may gradually increase your dose until your symptoms are controlled.
In some cases, the prescribed amount may be as high at 10 mg per day. The amount that could potentially lead to an overdose varies widely from person to person. It depends on many factors, including:.
In clinical studies in rats, the LD50 — the dose that caused half of the rats to die — ranged from to 2, mg per kilogram of body weight. This suggests that a person would have to take several thousand times the maximum prescribed dose to fatally overdose. Overdose is possible at any dose higher than your prescribed amount.
People older than 65 have an increased risk for serious side effects, including an overdose. Medications that inhibit CYP3A4 make it harder for your body to break down Xanax, which increases your risk of overdosing.
Drinking alcohol with Xanax also greatly increases your risk of having a lethal overdose. This includes over-the-counter OTC medications, vitamins, and other nutritional supplements. This will help your doctor choose the right medication and dosage to reduce your risk of drug interaction. Error Include a valid email address.
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This content does not have an English version. Additionally, a Xanax overdose can occur if taken with other benzodiazepines, alcohol, narcotics, and various other substances. Many people do this on purpose, which is a practice referred to as polydrug abuse or polydrug use. Frequently using more than one substance not only increases your risk of an overdose, but also facilitates addiction. Benzodiazepine addiction can destroy your health, relationships, career, and finances.
Substance use disorders are also chronic diseases that require professional care. Although Xanax overdose can be accidental, it can occur in people who have developed a tolerance to it and have to take higher doses to experience the same high.
A Xanax overdose is life-threatening. If someone is exhibiting the signs and symptoms of Xanax overdose, call immediately. Manufacturers in the United States no longer produce them, but they are generally present…. In this article, we examine the symptoms of poisoning from organophosphate, a form of insecticide. We also look at the risks and treatment options. Gasoline and gasoline vapors are toxic and can seriously damage a person's health. Learn more about the health effects of gasoline exposure here.
Anyone who may have overdosed on Prozac should receive emergency care, and most people fully recover. Here, learn about the symptoms and what to do. Small pieces of plastic called microplastics can travel through wastewater into the ocean, where animals may eat them. Learn about plastics in seafood…. What to know about Xanax overdose. Medically reviewed by Dena Westphalen, Pharm. What happens if you take too much? Share on Pinterest Drowsiness is one possible side effect of taking too much Xanax.
Drug interactions. Share on Pinterest A person should speak to their doctor about possible drug interactions before taking Xanax. What to do if someone has overdosed. Share on Pinterest A person should call the Poison Control helpline if they suspect that someone has taken too much Xanax. Exposure to air pollutants may amplify risk for depression in healthy individuals.
Costs associated with obesity may account for 3. Related Coverage. What to know about organophosphate poisoning. How does gasoline exposure affect a person's health? Can you overdose on Prozac, and what to do?
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